Synthesis of α-naphthylthiourea was written by Maruta, Seizaburo. And the article was included in Eisei Shikensho Hokoku in 1950.Application of 57293-19-3 This article mentions the following:
For synthesis of α-naphthylthiourea the method of Hatt and Troyahn has been modified. To 15 g. naphthalene in 15 g. glacial AcOH, is added 9.17 g. 83% HNO3 drop by drop at 40° with stirring, and the solution allowed to cool on standing to precipitate 18.2 g. α-nitronaphthalene. α-Nitronaphthalene (15 g.), 15.6 g. Fe dust, 4.5 g. H2O, 2 g. NaCl, and 0.3 g. 30% HCl, kept at 80-90° 2.5 hrs. with stirring, the solution made alk. with NaOH, extracted with benzene, evaporated, the residue dissolved in EtOH, and acidified with HCl to precipitate 13.9 g. α-naphthylamine-HCl. This (15 g.) in 45 ml. water is treated with 5-7.5 g. NH4CNS at 105° for 5 hrs. to yield 15.7-16.2 g. crystalline α-naphthylthiourea, m. 184° (from alc.). In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Application of 57293-19-3).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 57293-19-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary