Reaction of phosphoranes with formate esters. New method for synthesis of vinyl ethers was written by Subramanyam, Vinayakam;Silver, Eileen H.;Soloway, Albert H.. And the article was included in Journal of Organic Chemistry in 1976.Category: bromides-buliding-blocks This article mentions the following:
A reinvestigation of the Wittig reaction of phosphoranes with formate esters was undertaken with the purpose of developing a new method for synthesis of substituted vinyl ethers. Stabilized, partially stabilized, and reactive phosphoranes derived from (carbethoxymethyl)-, benzyl-, (3-methylbutyl)-, and (methoxymethyl)phosphonium halides were allowed to react with ethyl formate and vinyl ethers were isolated in the first three cases. Vinylidine diethers could not be prepared by this method. Thus, Ph3P:CHR (R = CO2Et, Ph, CH2CHMe2) reacted with HCO2Et to give the resp. EtOCH:CHR. In the experiment, the researchers used many compounds, for example, Isopentyltriphenylphosphonium bromide (cas: 28322-40-9Category: bromides-buliding-blocks).
Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary