Chiral Cyclopentadienyl Ligands Enable a Rhodium(III)-Catalyzed Enantioselective Access to Hydroxychromanes and Phthalides was written by Ye, Baihua;Cramer, Nicolai. And the article was included in Synlett in 2015.Recommanded Product: Methyl 3-bromo-5-hydroxybenzoate This article mentions the following:
The demand for efficient chiral cyclopentadienyl ligands (Cpx) has increased significantly in recent years, partly because Cp*Rh(III) species have been developed as powerful catalysts for directed C-H functionalization reactions. However, a lack of suitable Cpx ligands has hampered the development of the corresponding enantioselective processes. We report expansions of the libraries of two generations of Cpx ligands and their corresponding rhodium(I) complexes. The potential of the rhodium complexes as catalysts was evaluated in enantioselective C-H functionalizations involving cyclizations across tethered aldehydes. The mild reaction conditions permit the syntheses of hydroxychromanes and phthalides in good yields and high enantioselectivities. In the experiment, the researchers used many compounds, for example, Methyl 3-bromo-5-hydroxybenzoate (cas: 192810-12-1Recommanded Product: Methyl 3-bromo-5-hydroxybenzoate).
Methyl 3-bromo-5-hydroxybenzoate (cas: 192810-12-1) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Recommanded Product: Methyl 3-bromo-5-hydroxybenzoate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary