Month: January 2023

Solvolysis in hydrogen and deuterium oxide. IV. Halides with neighboring groups was written by Laughton, P. M.;Robertson, R. E.. And the article was included in Canadian Journal of Chemistry in 1961.Related Products of 4457-67-4 This article mentions the following:

Rate ratios k_D2O÷k_H2O were determined for 23 halides with HO, MeO, or halogen substituents, and compared to the data for Me₂CHBr at the same temperature The compounds fell into 3 classes: normal, including compounds showing no anchimeric assistance and the dihalides; low ratios, including compounds assisted by an adjacent HO group [HOCMe₂CH₂Cl (I) and Br, HOCMe₂CHMeCl and Br, and trans-cyclohexene bromohydrin]; high ratios, including HO(CH₂)₄Cl and compounds assisted by MeO group [MeO(CH₂)₄Cl (II) and Br, MeOCMe₂CH₂Br (III), and MeOCMe₂CHMeBr]. These results were attributed to differing effects on the solvent shell, resulting from involvement of the intramol. nucleophiles. In addition to b.p. and n_D of compounds studied, the following new preparations were reported (compound, b.p., n²⁵_D, and reagents used in preparation): HOCH₂CH₂I, 88° (30 mm.), 1.5625, NaI and HOCH₂CH₂Cl; MeO(CH₂)₃Br (IV), 129°, 1.4448 (26°), NaOMe and Br(CH₂)₃Br; MeO(CH₂)₃I, 155-8°, 1.4873 (27°), NaI and IV; I, 56° (40 mm.), 1.4260, Me₂C:CH₂ and HOCl in aqueous AcOH; II, 48-53° (20 mm.), 1.4290, NaOMe and Cl(CH₂)₄Cl; MeOCH₂CMe₂Cl, 88-90°, 1.4039 (24°), corresponding alc.; III, -, 1.4575, Me₂C:CH₂ and methanolic N-bromosuccinimide. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Related Products of 4457-67-4).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Related Products of 4457-67-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sources of carbon dioxide formed during coal pyrolysis was written by Chatterjee, Kuntal;Bal, Balkrishna;Stock, Leon M.;Zabransky, Robert F.. And the article was included in Energy & Fuels in 1989.SDS of cas: 57293-19-3 This article mentions the following:

The CO₂ yield in coal pyrolysis is not uniquely dependent on the concentration of carboxyl groups in the coal. Other O-containing functional groups or coal mineral matter contribute to CO₂ formation. These conclusions are drawn from the results from pyrolysis of Wyodak and Illinois Number 6 coals that were modified by removal of carboxylic acids or by the incorporation of aliphatic or aromatic esters or aromatic methoxy groups. The coals were selectively O-alkylated. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3SDS of cas: 57293-19-3).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.SDS of cas: 57293-19-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Inclusion function of heptakis[6-(alkylthio)-6-deoxy-2-O-sulfo]-β-cyclodextrins, cylindrical surfactants derived from β-cyclodextrin. A study by fluorescent probes was written by Takahashi, Hisao;Irinatsu, Yuichi;Tsujimoto, Munekazu;Kozuka, Seizi;Tagaki, Waichiro. And the article was included in Nippon Kagaku Kaishi in 1987.SDS of cas: 53784-83-1 This article mentions the following:

Title compounds were synthesized by selective modification of β-cyclodextrin (β-CD), as a novel class of anionic cylindrical surfactants. Their inclusion functions were studied in water by using fluorescent probes as the guests. Their binding ability for the neutral probe 1-phenylnaphthalene was more than 10-fold stronger than that of β-CD; it was independent of mol. aggregation of the surfactant monomer. Inclusion occurs at the inside of a hydrophobic cavity undergoing the strong influence of the electrostatic effect of anionic sulfate groups and the effect of the chain length of the alkylthio groups. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1SDS of cas: 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.SDS of cas: 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Photochemistry of N-(selenoalkyl)-phthalimides. Formation of N, Se-heterocyclic systems was written by Oksdath-Mansilla, Gabriela;Heredia, Adrian A.;Arguello, Juan E.;Penenory, Alicia B.. And the article was included in Photochemical & Photobiological Sciences in 2015.Computed Properties of C13H14BrNO2 This article mentions the following:

A variety of N-(selenomethyl)alkyl-phthalimides (alkyl = -(CH₂)_n, n = 2-5) and N-(selenobenzyl)propyl phthalimide were synthesized and their photochem. was studied at λ = 300 nm. Steady-state photolysis and laser time-resolved spectroscopy studies confirmed that these reactions proceeded by direct or acetone-sensitized excitation followed by intramol. electron transfer (ET) between Se atom and the phthalimide moiety. Two main pathways are possible after ET, proton transfer to the ketyl radical anion from the CH₃Se^+. or the -CH₂Se^+.– moieties, yielding the corresponding biradicals. Collapse of these biradicals yields cyclization products with the resp. endo or exo selenium-containing heterocycles. Competition between both proton transfer processes depends on the chain length of the alkyl spacer between the phthalimide and Se groups as well as the size of the cycle being formed. In the experiment, the researchers used many compounds, for example, N-(5-Bromopentyl)phthalimide (cas: 954-81-4Computed Properties of C13H14BrNO2).

N-(5-Bromopentyl)phthalimide (cas: 954-81-4) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Computed Properties of C13H14BrNO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Mechanism and solvent reorganization accompanying hydrolyses of anchimerically assisted alkyl halides in water was written by Blandamer, Michael J.;Golinkin, G. S.;Robertson, Ross E.. And the article was included in Journal of the American Chemical Society in 1969.Application In Synthesis of 1-Bromo-4-methoxybutane This article mentions the following:

This paper deals with the problem of solvent reorganization, anchimeric assistance, and mechanism for hydrolysis of 9 alkyl halides where the neighboring group is -OH, -OMe, or -SMe. By using the temperature coefficient of the enthalpy as a gauge of relative solvent reorganization, we show that the transition state in the hydrolysis of those alkyl halides giving evidence of anchimeric assistance resembles that for an SN1 mechanism. This conclusion was supported in one case by 13C labeling experiments in spite of product analysis seemingly favoring SN2 nucleophilic displacement by the solvent. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Application In Synthesis of 1-Bromo-4-methoxybutane).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Application In Synthesis of 1-Bromo-4-methoxybutane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Iron-catalyzed C(sp²)-H alkylation of carboxamides with primary electrophiles was written by Monks, Brendan M.;Fruchey, Erin R.;Cook, Silas P.. And the article was included in Angewandte Chemie, International Edition in 2014.Electric Literature of C5H11BrO This article mentions the following:

A robust iron-catalyzed ortho alkylation of aryl amides was carried out. The reaction generally proceeds in high yields with exceptional regioselectivity. The reaction is complete in less than 10 min and can be performed in bio-derived 2-methyltetrahydrofuran as solvent on gram scale. The reactivity and selectivity provides a reaction profile unique among the reported C-H functionalization reactions, thereby complementing current strategies. The low cost and toxicity of the reagents should simplify the large-scale implementation of this C-H functionalization. Moreover, mechanistic experiments indicate that substrate coordination is irreversible and occurs prior to C-H cleavage. Further efforts will be directed toward mechanistic understanding and expanding the scope of this interesting transformation. © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Electric Literature of C5H11BrO).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Electric Literature of C5H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

An Iodine-Catalyzed Hofmann-Loeffler Reaction was written by Martinez, Claudio;Muniz, Kilian. And the article was included in Angewandte Chemie, International Edition in 2015.Application In Synthesis of 1-(2-Bromoethyl)-4-methoxybenzene This article mentions the following:

Iodine reagents have been identified as economically and ecol. benign alternatives to transition metals, although their application as mol. catalysts in challenging C-H oxidation reactions has remained elusive. An attractive iodine oxidation catalysis is now shown to promote the convenient conversion of carbon-hydrogen bonds into carbon-nitrogen bonds with unprecedented complete selectivity. The reaction proceeds by two interlocked catalytic cycles comprising a radical chain reaction, which is initiated by visible light as energy source. This unorthodox synthetic strategy for the direct oxidative amination of alkyl groups has no biosynthetic precedence and provides an efficient and straightforward access to a general class of saturated nitrogenated heterocycles, i.e. I. In the experiment, the researchers used many compounds, for example, 1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0Application In Synthesis of 1-(2-Bromoethyl)-4-methoxybenzene).

1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application In Synthesis of 1-(2-Bromoethyl)-4-methoxybenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bimetal Cooperatively Catalyzed Arylalkynylation of Alkynylsilanes was written by Chen, Xing;Li, Mengke;Liu, Zhipeng;Yang, Can;Xie, Haisheng;Hu, Xinwei;Su, Shi-Jian;Jiang, Huanfeng;Zeng, Wei. And the article was included in Organic Letters in 2021.Recommanded Product: 61150-57-0 This article mentions the following:

An unprecedented Pd/Rh cooperatively catalyzed arylalkynation of alkynylsilanes I (X = CH₂, CH₂CH₂, CHMeCH₂; R = Me, Ph; R¹ = n-pentyl, Ph, 4-MeOC₆H₄, etc.; R² = H, 4-Cl, 4-Me, 5-F) with propargylic alcs. R³CCCMe₂OH (R³ = Ph, 4-FC₆H₄, 1-naphthyl, 2-thienyl, 3-pyridinyl, etc.) has been developed to prepare alkynylidene-containing benzosilacycles II. These silaarenes II possess a particular aggregation-induced emission behavior. Mechanistic investigations demonstrated that the relay trimetallic transmetalation plays a pivotal role in governing this transformation. In the experiment, the researchers used many compounds, for example, 2-Bromo-4-fluorobenzylbromide (cas: 61150-57-0Recommanded Product: 61150-57-0).

2-Bromo-4-fluorobenzylbromide (cas: 61150-57-0) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Recommanded Product: 61150-57-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Pillar[5]arenes modified tetraphenylethylene as fluorescent chemosensor for paraquat detection was written by Kang, Zuzhe;Yang, Jiao;Jiang, Jingjing;Zhao, Li;Zhang, Yanrong;Tu, Qin;Wang, Jinyi;Yuan, Mao-Sen. And the article was included in Sensors and Actuators, B: Chemical in 2022.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione This article mentions the following:

Pesticide pollution has become a severe challenge for harming food quality and human safety. Therefore, it′s urgent to develop sensitive methods to detect and analyze pesticides. Herein, we successfully developed a new turn-on fluorescent chemosensor (TPE-4P), a tetra-Ph ethylene derivative modified with four pillar[5]arenes, which could sensitively, selectively, and rapidly detect the pesticide paraquat. In our study, we took full advantage of both the host-guest strategy and aggregation-induced emission (AIE) to achieve fluorescent enhancement of the chemosensor for paraquat, in which four pillar[5]arenes as the recognition units can selectively capture paraquat. The formation of the supramol. complexes based on the interlaced host-guest interactions effectively restricted the intramol. single-bond rotation and skeletal vibration, resulting in the intensive fluorescent emission. The detection limit for paraquat was low enough to reach 154.1 nM, and the detection time was short enough to meet the rapid detection conditions. Moreover, the test strips loaded-TPE-4P facilitated the detection process and achieved the semi-quant. anal. for paraquat in real spiked samples. In addition, TPE-4P could respond to paraquat in living zebrafish obviously. These results suggest that the cooperation of host-guest and AIE chem. could become useful for the design to detect some appropriate organic mols. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Application In Synthesis of 1-Bromopyrrolidine-2,5-dione).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of new pyrrole-pyridine-based ligands using an in situ Suzuki coupling method was written by Boettger, Matthias;Wiegmann, Bjoern;Schaumburg, Steffen;Jones, Peter G.;Kowalsky, Wolfgang;Johannes, Hans-Hermann. And the article was included in Beilstein Journal of Organic Chemistry in 2012.Related Products of 22426-14-8 This article mentions the following:

The compounds 6-(pyrrol-2-yl)-2,2′-bipyridine, 2-(pyrrol-2-yl)-1,10-phenanthroline and 2-(2-(N-methylbenz[d,e]imidazole))-6-(pyrrol-2-yl)pyridine were synthesized by using an in situ generated boronic acid for the Suzuki coupling. Crystals of the products could be grown and exhibited interesting structures by X-ray anal., one of them showing a chain-like network with the adjacent mols. linked to each other via intermol. N-H···N hydrogen bonds. In the experiment, the researchers used many compounds, for example, 2-Bromo-1,10-phenanthroline (cas: 22426-14-8Related Products of 22426-14-8).

2-Bromo-1,10-phenanthroline (cas: 22426-14-8) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Related Products of 22426-14-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary