Effect of intermolecular interaction on the reaction of bromination in the binary system benzene-nitrobenzene was written by Cheshko, F. F.;Novikova, L. N.;Shevchenko, O. I.. And the article was included in Zhurnal Obshchei Khimii in 1957.Synthetic Route of C10H13BrO This article mentions the following:
Bromination of a 2:5 molar mixture of C6H6 and PhNO2 4 hrs. on a steam bath with 0.3 mole Br per 0.36 mole C6H6 occurred rapidly and in 90 min. gave 33.1% PhBr without any Br2C6H4; a kinetic curve of the reaction was shown. In CCl4 the reaction failed to take place after 4 hrs. When the solvent was omitted, the reaction was very slow for 1.5 hrs., then proceeded at an appreciable rate and gave 10.3% PhBr in 4 hrs. The reaction in PhBr was less rapid than in PhNO2 but more rapid than without a solvent and gave 15.3% PhBr in 4 hrs. The solvating or complexing action of PhNO2 on C6H6 accounted for the activation of the reaction described above. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Synthetic Route of C10H13BrO).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Synthetic Route of C10H13BrO
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary