Chiral Chalcogenide-Catalyzed Enantioselective Electrophilic Hydrothiolation of Alkenes was written by Liang, Yaoyu;Jiao, Hui;Zhang, Hang;Wang, You-Qing;Zhao, Xiaodan. And the article was included in Organic Letters in 2022.Related Products of 128-08-5 This article mentions the following:
A new strategy for the construction of chiral sulfides by catalytic enantioselective hydrothiolation of alkenes via an electrophilic pathway has been developed. Using this strategy, cyclic and acyclic unactivated alkenes efficiently afforded various chiral products in the presence of electrophilic sulfur reagents and silanes through chiral chalcogenide catalysis. The obtained products were easily transformed into other types of valuable chiral sulfur-containing compounds Mechanistic studies revealed that the superior construction of chiral thiiranium ion intermediate is the key to achieving such a transformation. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Related Products of 128-08-5).
1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Related Products of 128-08-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary