Metal free synthesis of 1,3-diynes through Csp-Csp homo- and hetero-coupling reaction of terminal alkynes was written by Tamuli, Kashyap J.;Bordoloi, Manobjyoti. And the article was included in Sustainable Chemistry and Pharmacy in 2022.Recommanded Product: 128-08-5 This article mentions the following:
Recent methodologies aimed at utilization of eco-friendly pathways and sustainable chem. has turned out to be a convergent point in chem. research. With an objective to derive an economical, greener approach, herein, authors report a mild and straightforward synthetic strategy to synthesize a series of substituted sym. and unsym. 1,3-diyne derivatives This metal free synthetic route catalyzed by N-Bromosuccinimide with tBuOK and KF as fluorine source at room temperature affords excellent yields up to 95% within 2 h. Such type of a greener and sustainable process was adopted for the development of organic building blocks or compounds with minimal waste afford to define the most of the green chem. principles. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Recommanded Product: 128-08-5).
1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 128-08-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary