Boulange, Agathe et al. published their research in Bioorganic & Medicinal Chemistry in 2015 | CAS: 108940-96-1

3,5-Dibromo-4-methoxybenzaldehyde (cas: 108940-96-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 108940-96-1

Synthesis and antibacterial activities of cadiolides A, B and C and analogues was written by Boulange, Agathe;Parraga, Javier;Galan, Abraham;Cabedo, Nuria;Leleu, Stephane;Sanz, Maria Jesus;Cortes, Diego;Franck, Xavier. And the article was included in Bioorganic & Medicinal Chemistry in 2015.Application of 108940-96-1 This article mentions the following:

A one-pot multicomponent synthesis of natural butenolides named cadiolides A, B, C and analogs has been realized. An antibacterial structure activity relationship shows that the presence of phenolic hydroxyl groups and the number and position of bromine atoms on the different aromatic rings are important features for antibacterial activity, besides it was demonstrated the tolerance of both benzene and furan ring at position 3 of the butenolide nucleus. Furthermore, none of the most relevant antibacterial compounds showed any cytotoxicity in freshly isolated human neutrophils. The synthesis of the target compounds was achieved using 6-(4-methoxyphenyl)-2,2-dimethyl-4H-1,3-dioxin-4-one derivatives and 6-(2-furanyl)-2,2-dimethyl-4H-1,3-dioxin-4-one as key intermediates. The title compounds thus formed included (5Z)-3-(4-hydroxybenzoyl)-4-(4-hydroxyphenyl)-5-[(4-hydroxyphenyl)methylene]-2(5H)-furanone derivatives, (5Z)-3-(3,5-dibromo-4-hydroxybenzoyl)-4-(3,5-dibromo-4-hydroxyphenyl)-5-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2(5H)-furanone (i.e., cadiolide B). In the experiment, the researchers used many compounds, for example, 3,5-Dibromo-4-methoxybenzaldehyde (cas: 108940-96-1Application of 108940-96-1).

3,5-Dibromo-4-methoxybenzaldehyde (cas: 108940-96-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 108940-96-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary