In 2017,Paradiso, Veronica; Bertolasi, Valerio; Costabile, Chiara; Caruso, Tonino; Dabrowski, Michal; Grela, Karol; Grisi, Fabia published 《Expanding the Family of Hoveyda-Grubbs Catalysts Containing Unsymmetrical NHC Ligands》.Organometallics published the findings.Electric Literature of C9H11Br The information in the text is summarized as follows:
Hoveyda-Grubbs 2nd-generation catalysts containing N-alkyl/N’-aryl N-heterocyclic carbene (NHC) ligands were synthesized and studied in representative olefin metathesis reactions. Steric perturbations of unsym. NHCs were achieved through modulation of the hindrance of alkyl (neopentyl, neophyl, cyclohexyl) and aryl (2-isopropylphenyl, mesityl) substituents at the N atoms in combination with different backbone configurations (syn and anti). The NHC substitution patterns strongly influence the stability and reactivity of the corresponding complexes. In general, complexes bearing an anti NHC backbone are more stable and more active than their corresponding syn isomers. In both the series, the presence of bulky, highly branched N-alkyl groups tends to give reduced catalytic differences between syn and anti isomers, whereas the nature of the N’-aryl substituent (2-isopropylphenyl or mesityl) gives rise to different activity and/or selectivity. Of note, an N’-mesityl catalyst with anti backbone is highly competent in the ethenolysis of Et oleate, achieving up to 90% selectivity for the formation of terminal olefins. After reading the article, we found that the author used 1-Bromo-2-isopropylbenzene(cas: 7073-94-1Electric Literature of C9H11Br)
1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Electric Literature of C9H11Br
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary