The author of 《Synthesis of 18F-difluoromethylarenes using arylboronic acids, ethyl bromofluoroacetate and [18F]fluoride》 were Sap, Jeroen B. I.; Wilson, Thomas C.; Kee, Choon Wee; Straathof, Natan J. W.; am Ende, Christopher W.; Mukherjee, Paramita; Zhang, Lei; Genicot, Christophe; Gouverneur, Veronique. And the article was published in Chemical Science in 2019. Application of 401-55-8 The author mentioned the following in the article:
Herein, the radiosynthesis of 18F-difluoromethylarenes RCHF18F (R = 4-C2H5, 4-OC6H5, 3,5-CH3, etc.) via the assembly of three components, a boron reagent, Et bromofluoroacetate, and cyclotron-produced non-carrier added [18F]fluoride was reported. The two key steps are a copper-catalyzed cross-coupling reaction, and a Mn-mediated 18F-fluorodecarboxylation. In the experiment, the researchers used many compounds, for example, Ethylbromofluoroacetate(cas: 401-55-8Application of 401-55-8)
Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.Application of 401-55-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary