Zhang, Huihui; Kou, Luyao; Chen, Dong; Ji, Meishan; Bao, Xiaoguang; Wu, Xinxin; Zhu, Chen published their research in Organic Letters on August 7 ,2020. The article was titled 《Radical-Mediated Distal Ipso-Migration of O/S-Containing Heteroaryls and DFT Studies for Migratory Aptitude》.COA of Formula: C4H6BrFO2 The article contains the following contents:
Herein we describe an efficient distal ipso-migration of O- and S-containing heteroaryls and the radical heteroarylation of unactivated alkenes. The migration is triggered by various fluoroalkyl radicals, leading to valuable multifunctionalized ketones. The comparisons of migratory aptitude for O-/S-containing heteroaryls are comprehensively investigated. The origin of the chemoselective migration could be partially attributed to the discrepancy in the energy level of the LUMO of each heteroaryl group. The results came from multiple reactions, including the reaction of Ethylbromofluoroacetate(cas: 401-55-8COA of Formula: C4H6BrFO2)
Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.COA of Formula: C4H6BrFO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary