The author of 《Site-selective C-H activation and regiospecific annulation using propargylic carbonates》 were Lu, Qingquan; Mondal, Shobhan; Cembellin, Sara; Gressies, Steffen; Glorius, Frank. And the article was published in Chemical Science in 2019. Product Details of 586-76-5 The author mentioned the following in the article:
An unprecedented RuII-catalyzed site-selective and regiospecific annulation of benzoic acids ArC(O)OH (2-CH3C6H4, thiophen-2-yl, 1-methyl-1H-indol-3-yl, etc.) with propargylic carbonates R1CCC(R2)(R3)(OCO2CH3) [R1 = C6H5, thiophen-3-yl; R2 = Me, Et, n-propyl; R3 = Me, Et; R2R3 = -(CH2)4-] has been described. The weakly coordinating carboxylic acid moiety outperformed other typically used directing groups in C-H activation, including ketone, nitrile, sulfonamide, amide and strongly coordinating nitrogen heterocycles. This is an important step towards the application of C-H activation reactions in complex (functional) real-world mols.4-Bromobenzoic acid(cas: 586-76-5Product Details of 586-76-5) was used in this study.
4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.Product Details of 586-76-5 It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary