Product Details of 401-55-8On September 24, 2021 ,《The serendipitous effect of KF in Ritter reaction: Photo-induced amino-alkylation of alkenes》 was published in iScience. The article was written by Guan, Yu-Qing; Min, Xiang-Ting; He, Gu-Cheng; Ji, Ding-Wei; Guo, Shi-Yu; Hu, Yan-Cheng; Chen, Qing-An. The article contains the following contents:
The Ritter reaction has been recognized as an elegant strategy to construct the C-N bond. Its key feature is forming the carbocation for nucleophilic attack by nitriles. Herein, authors report a complementary visible-light-induced three-component Ritter reaction of alkenes, nitriles, and α-bromo nitriles/esters, thereby providing mild and rapid access to various γ-amino nitriles/acids. Mechanistic studies indicated that traceless fluoride relay, transforming KF into imidoyl fluoride intermediate, is critical for the efficient reaction switch from atom transfer radical addition (ATRA) to the Ritter reaction. This approach to amino-alkylation of alkenes is chemoselective and operationally simple. In addition to this study using Ethylbromofluoroacetate, there are many other studies that have used Ethylbromofluoroacetate(cas: 401-55-8Product Details of 401-55-8) was used in this study.
Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.Product Details of 401-55-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary