Zhang, Qing-Yang published the artcileOne pot synthesis of dibenzodiazepinones via CuI catalysis in ethylene glycol, Recommanded Product: Ethyl 2-bromo-4-fluorobenzoate, the main research area is halobenzoate phenylenediamine cyclization copper catalyst ethylene glycol; dibenzodiazepinone preparation.
A one-pot protocol for the synthesis of dibenzodiazepinones was developed. Substituted Et 2-halobenzoates are cross-coupled with 1,2-phenylenediamine utilizing a ligand-free, CuI-catalyzed system, which spontaneously undergo intramol. N-acylation in ethylene glycol to give the corresponding products in high yields. This synthetic protocol provides a concise and efficient access to a wide variety of dibenzodiazepinones, including biol. active mols.
Chinese Chemical Letters published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 651341-68-3 belongs to class bromides-buliding-blocks, name is Ethyl 2-bromo-4-fluorobenzoate, and the molecular formula is C9H8BrFO2, Recommanded Product: Ethyl 2-bromo-4-fluorobenzoate.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary