Liu, Chao published the artcilePalladium-Catalyzed Arylative Dearomatization and Subsequent Aromatization/Dearomatization/Aza-Michael Addition: Access to Zephycarinatine and Zephygranditine Skeletons, Recommanded Product: 2-Bromo-4-methoxybenzoic acid, the main research area is zephycarinatine scaffold synthesis; zephygranditine scaffold synthesis; palladium catalyzed arylative dearomatization Ugi adduct chemoselective stereoselective.
We have developed a novel palladium-catalyzed arylative dearomatization and subsequent aromatization/dearomatization/aza-Michael addition process of Ugi adducts, enabling the rapid construction of diverse zephycarinatine and zephygranditine scaffolds containing two adjacent quaternary carbon stereocenters with excellent chemoselectivity and stereoselectivity in a rapid, step-economical, and highly efficient manner. This approach shows broad substrate scope and excellent functional-group tolerance with diverse electron-rich and electron-deficient aromatic substrates. The synthetic utility of this method is further demonstrated by versatile transformations of the products.
Organic Letters published new progress about Alkaloids Role: SPN (Synthetic Preparation), PREP (Preparation) (plicamine). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Recommanded Product: 2-Bromo-4-methoxybenzoic acid.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary