Bauer, Daniel published the artcileFunctionalisable acyclic cucurbiturils, Computed Properties of 55788-44-8, the publication is Organic Chemistry Frontiers (2019), 6(10), 1555-1560, database is CAplus.
Synthetic strategies were described to prepare acyclic cucurbituril derivatives with two different types of appended functional groups, one that mediates water solubility and another one that allows further functionalization. The synthesis started with the coupling of a 1,4-disubstituted naphthalene derivative containing one 2-chloroethoxy and one 3-sulfonatopropoxy group to a suitable tetrameric glycoluril-derived precursor. This reaction afforded two regioisomers, differing in the relative orientation of the peripheral substituents, which could be separated in a straightforward fashion and structurally characterized. Both isomers were then converted into the corresponding diazides and diamines that served to append further residues by, resp., copper(I)-catalyzed azide-alkyne cycloaddition or amide formation. Binding studies showed that the functionalized dianionic acyclic cucurbiturils thus obtained possess a notable cation affinity in water, albeit a lower one than an analog with four peripheral neg. charged substituents. This work constitutes the basis for the development of water-soluble acyclic cucurbiturils whose applications could potentially go beyond the use as receptors.
Organic Chemistry Frontiers published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Computed Properties of 55788-44-8.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary