Cui, Ning’s team published research in Organic Letters in 24 | CAS: 111-83-1

Organic Letters published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Application In Synthesis of 111-83-1.

Cui, Ning published the artcileNickel-Catalyzed Reductive Coupling of γ-Metalated Ketones with Unactivated Alkyl Bromides, Application In Synthesis of 111-83-1, the publication is Organic Letters (2022), 24(22), 3987-3992, database is CAplus and MEDLINE.

A nickel-catalyzed reductive cross-coupling reaction of aryl cyclopropyl ketones with easily accessible unactivated alkyl bromides to access aryl alkyl ketones was developed. This strategy facilitated access to various of γ-alkyl substituted ketones via ring opening of cyclopropyl ketones (26 examples, 50-90% yield). Initial mechanistic studies revealed that the reaction proceeds via a radical cleavage of the alkyl bromide.

Organic Letters published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Application In Synthesis of 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary