Zhang, Yan published the artcileCopper-Catalyzed Radical Cascade Difluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes: A Route to Difluoromethylated Naphthoquinones, Application of Ethylbromofluoroacetate, the publication is Journal of Organic Chemistry (2017), 82(13), 6811-6818, database is CAplus and MEDLINE.
A novel copper-catalyzed cascade difluoromethylation/cyclization of 2-(3-arylpropioloyl)benzaldehydes has been developed. This method affords an efficient and straightforward access to structurally diverse difluoromethylated naphthoquinones in one pot, starting from readily available starting materials. The reaction represents the first trans-acyldifluoromethylation of internal alkynes, which features aldehydes as acceptors for the addition of alkenyl radicals. Furthermore, this protocol can also access monofluoromethylated naphthoquinones and difluoromethylated indanones with the same reaction conditions.
Journal of Organic Chemistry published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C15H10O2, Application of Ethylbromofluoroacetate.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary