Earle, Martyn J. published the artcileSynthesis and evaluation of a designed inhibitor for nonactin biosynthesis in S. griseus ETH A7796, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Bioorganic & Medicinal Chemistry Letters (1997), 7(17), 2187-2192, database is CAplus.
A designed suicide inhibitor of a postulated, enzyme-catalyzed step in the biosynthesis of the macrotetrolide antibiotic nonactin was synthesized and evaluated in vivo. The inhibitor reduced the rate of nonactin biosynthesis by >75% while affecting neither biomass production nor the synthesis of other secondary metabolites. The role of the inhibitor in nonactin biosynthesis is discussed.
Bioorganic & Medicinal Chemistry Letters published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary