Synergistic Effect: Hydroalkoxylation of Allenes through Combination of Enantiopure BIPHEP-Gold Complexes and Chiral Anions was written by Aikawa, Kohsuke;Kojima, Masafumi;Mikami, Koichi. And the article was included in Advanced Synthesis & Catalysis in 2010.Category: bromides-buliding-blocks This article mentions the following:
A synergistic effect is observed for the combination of neutral dinuclear gold complex I (R1 = 3,5-di-MeC6H3) with chiral silver phosphate II in the intramol. hydroalkoxylation of allenes to give vinyltetrahydrofuran derivatives in high yields and enantioselectivities. The monocationic dinuclear gold complex affords higher catalytic activity and enantioselectivity than the neutral or dicationic digold complexes. The synergistic effect is thus highly promising to provide a guiding principle in designing an efficient chiral environment for creating an asym. catalyst. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Category: bromides-buliding-blocks).
4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary