Li, Tian-wen et al. published their research in Yaoxue Xuebao in 2012 | CAS: 96558-78-0

3-Bromo-5-chlorophenylamine (cas: 96558-78-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.HPLC of Formula: 96558-78-0

Design, synthesis and biological evaluation of multi-substituted N-phenyl-2,2-dichloro acetamide analogues as anti-cancer drugs was written by Li, Tian-wen;Yang, Yong-chong;Cheng, Chang-mei;Wang, Dong-chun;Lu, Ai-jun;Zhao, Yu-fen. And the article was included in Yaoxue Xuebao in 2012.HPLC of Formula: 96558-78-0 This article mentions the following:

Our earlier research has shown that mono-substituted N-phenyl-2,2-dichloro acetamide exhibits much higher anti-cancer activity than the lead compound sodium dichloro acetate (DCA). In this paper, a variety of multi-substituted N-phenyl-2, 2-dichloro acetamide were synthesized and biol. evaluated. The results showed that 3,5-disubstituted N-phenyl-2,2-dichloro acetamide analogs had satisfactory potency. Among them, N-(3,5-diiodophenyl)-2,2-dichloroacetamide had an IC50 of 2.84 μmol·L-1 against non-small cell lung cancer cell line A549 and could induce cancer cell apoptosis. In the experiment, the researchers used many compounds, for example, 3-Bromo-5-chlorophenylamine (cas: 96558-78-0HPLC of Formula: 96558-78-0).

3-Bromo-5-chlorophenylamine (cas: 96558-78-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.HPLC of Formula: 96558-78-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary