Pd-catalyzed C-S cyclization via C-H functionalization strategy: access to sulfur-containing benzoheterocyclics was written by Chen, Shihao;Wang, Ming;Jiang, Xuefeng. And the article was included in Chinese Journal of Chemistry in 2018.Recommanded Product: 1-(2-Bromoethyl)-4-methoxybenzene This article mentions the following:
An efficient method was developed for the synthesis of functionalized dihydrobenzothiophenes I [R = H, OMe; R1 = H, Me, NO2; R2 = H, Me, F; R3 = H, OMe; R4 = H; R5 = H, Et, Ph; R1R2 = OCH2O; R4R5 = (CH2)4] and thiochromans II [R6 = H, 7-t-Bu, 5-MeO; R7 = CO2Et, C(O)O-i-Pr] via Pd-catalyzed C-H functionalization/C-S cyclization of thioacetates. Mechanistic studies indicated that C-H bond cleavage was involved in the rate-determining step. Furthermore, new pathways for the synthesis of semiconductor materials BTBT and BTT demonstrated the great potential of this protocol. In the experiment, the researchers used many compounds, for example, 1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0Recommanded Product: 1-(2-Bromoethyl)-4-methoxybenzene).
1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 1-(2-Bromoethyl)-4-methoxybenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary