Chemical screening of novel strigolactone agonists that specifically interact with DWARF14 protein was written by Yasui, Rei;Seto, Yoshiya;Ito, Shinsaku;Kawada, Kojiro;Itto-Nakama, Kaori;Mashiguchi, Kiyoshi;Yamaguchi, Shinjiro. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2019.Application of 615-55-4 This article mentions the following:
Strigolactones (SLs) are a class of plant hormones that regulate shoot branching as well as being known as root-derived signals for parasitic and symbiotic interactions. The phys. interaction between SLs and the DWARF14 (D14) receptor family can be examined by differential scanning fluorimetry (DSF) that monitors the changes in protein melting temperature (Tm). The Tm of D14 is lowered by bioactive SLs in DSF anal. In this report, we screened the compounds that lower the Tm of Arabidopsis D14 (AtD14) as potential candidates for SL agonists using DSF anal. Subsequent physiol. analyzes revealed that 113D10 acts as a novel SL agonist in a D14-dependent manner. Intriguingly, 113D10 has a chem. structure different from natural SLs in that it does not possess an enol ether bond that connects to a methylbutenolide moiety. Moreover, 113D10 does not stimulate seed germination of root parasitic plants. Accordingly, 113D10 can be a useful tool for SL studies and agricultural applications. In the experiment, the researchers used many compounds, for example, 3,4-Dibromoaniline (cas: 615-55-4Application of 615-55-4).
3,4-Dibromoaniline (cas: 615-55-4) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Application of 615-55-4
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary