Synthesis of N-phenyl-2-[1,4,5,8-14C]naphthylamine, N-phenyl-2-[8-13C]naphthylamine, and N-[U-14C]phenyl-2-naphthylamine was written by Walker, G. H.;Hathway, D. E.. And the article was included in Journal of Labelled Compounds and Radiopharmaceuticals in 1976.Product Details of 57293-19-3 This article mentions the following:
2-PhNHC10H7-8-13C (I) was prepared in 8 steps and in >30% overall yieldfrom 4-MeOC6H4(CH2)2Br, the synthesis involving cyclization of 4-MeOC6H4(CH2)313CO2H. I had a 5.5 atom % enrichment of 13C. 2-PhNHC10H7-1,4,5,8-14C4 and 2-PhNHC10H7-Ph-U-14C were prepared from 2-naphthol-1,4,5,8-14C4 and PhNH2 and from 2-naphthol and PhNH2-U-14C, resp. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Product Details of 57293-19-3).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Product Details of 57293-19-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary