Clofelin analogs containing difluoromethoxy groups was written by Yagupol’skii, L. M.;Fialkov, Yu. A.;Tarasova, E. V.. And the article was included in Pharmaceutical Chemistry Journal in 2006.Related Products of 76361-99-4 This article mentions the following:
A series of 2-(2-chloro- or 2-bromo-6-difluoromethoxyphenylamino)imidazoline I (X = Cl or Br) hydrochlorides – clofelin analogs containing difluoromethoxy groups – have been synthesized. The introduction of difluoromethoxy groups decreased the toxicity, increased the duration of hypotensive action, and induced a less pronounced decrease in the heart rate in comparison to the action of clofelin. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-nitrophenol (cas: 76361-99-4Related Products of 76361-99-4).
3-Bromo-2-nitrophenol (cas: 76361-99-4) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Related Products of 76361-99-4
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary