Antioxidant and antiinflammatory activity of new water-soluble sulfur-containing phenolic compounds was written by Zenkov, N. K.;Menshchikova, E. B.;Kandalintseva, N. V.;Oleynik, A. S.;Prosenko, A. E.;Gusachenko, O. N.;Shklyaeva, O. A.;Vavilin, V. A.;Lyakhovich, V. V.. And the article was included in Biochemistry (Moscow) in 2007.Recommanded Product: 1-(3-Bromopropyl)-4-methoxybenzene This article mentions the following:
We synthesized a series of structurally related water-soluble alkyl phenols – sodium 4-hydroxyphenyl Pr sulfonates and thiosulfonates with different number of tert-Bu groups at the ortho-position. In exptl. systems of transient metal-induced Et oleate and low-d. lipoprotein oxidation the antioxidant activity of the compounds increased when the tert-Bu group number at the ortho-position increased and when the sulfonate group was replaced with thiosulfonate. Compounds containing thiosulfonate group in para-Pr substituent also more effectively inhibited reactive oxygen metabolites generated in xanthine-xanthine oxidase system and during morpholinosydnonimine decomposition compared to sulfonate-containing analogs. Phenols with one tert-Bu group at the ortho-position have been shown to exhibit the highest antiinflammatory activity in the model of carrageenan-induced rat paw inflammation, as well as with regard to the expression of the glutathione S-transferase P1-1 gene in HepG2 human hepatoma cell line. Thus, it can be reasonably speculated that the antiinflammatory activity of sulfur-containing phenolic antioxidants in vivo is mediated by their effect on redox-sensitive transcription factors. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Recommanded Product: 1-(3-Bromopropyl)-4-methoxybenzene).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Recommanded Product: 1-(3-Bromopropyl)-4-methoxybenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary