Generation of Iminyl Copper Species from α-Azido Carbonyl Compounds and Their Catalytic C-C Bond Cleavage under an Oxygen Atmosphere was written by Chiba, Shunsuke;Zhang, Line;Ang, Gim Yean;Hui, Benjamin Wei-Qiang. And the article was included in Organic Letters in 2010.Formula: C10H11BrO2 This article mentions the following:
A copper-catalyzed reaction of α-azidocarbonyl compounds under an oxygen atm. is reported where nitriles are formed via C-C bond cleavage of a transient iminyl copper intermediate. The transformation is carried out by a sequence of denitrogenative formation of iminyl copper species from α-azidocarbonyl compounds and their C-C bond cleavage, where mol. oxygen (1 atm) is a prerequisite to achieve the catalytic process and one of the oxygen atoms of O2 was found to be incorporated into the β-carbon fragment as a carboxylic acid. In the experiment, the researchers used many compounds, for example, Ethyl (2-bromophenyl)acetate (cas: 2178-24-7Formula: C10H11BrO2).
Ethyl (2-bromophenyl)acetate (cas: 2178-24-7) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbonbromine bond is electrophilic in nature. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Formula: C10H11BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary