Pattern-based recognition of heparin contaminants by an array of self-assembling fluorescent receptors was written by Jagt, Richard B. C.;Gomez-Biagi, Rodolfo F.;Nitz, Mark. And the article was included in Angewandte Chemie, International Edition in 2009.Quality Control of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin This article mentions the following:
Tracking down potential killers: Strong host-guest interactions enable the facile combination of polycationic cyclodextrin binding motifs (blue) with fluorescent reporters (orange) tethered to a hydrophobic guest mol. (dark green). An array of supramol. fluorescent receptors prepared by this modular approach was used for the pattern-based recognition of neg. charged contaminants in the anticoagulant drug heparin. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Quality Control of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin).
Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Quality Control of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary