Dendritic Cell Lectin-Targeting Sentinel-like Unimolecular Glycoconjugates To Release an Anti-HIV Drug was written by Zhang, Qiang;Su, Lu;Collins, Jennifer;Chen, Guosong;Wallis, Russell;Mitchell, Daniel A.;Haddleton, David M.;Becer, C. Remzi. And the article was included in Journal of the American Chemical Society in 2014.Recommanded Product: 53784-83-1 This article mentions the following:
A series of cyclodextrin-based glycoconjugates, including glycoclusters and star glycopolymers, were synthesized via combination of CuAAC Huisgen coupling and copper-mediated living radical polymerization These glycoconjugates showed high affinity binding to the human transmembrane lectin DC-SIGN and act as inhibitors to prevent the binding of HIV envelope protein gp120 to DC-SIGN at nanomolar concentrations The star block glycopolymers showed high loading capacity of hydrophobic anticancer and anti-HIV drugs, indicating promising applications in HIV-therapeutic and smart drug delivery. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Recommanded Product: 53784-83-1).
Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Recommanded Product: 53784-83-1
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary