Antibacterial activities of fluorescent nano assembled triphenylamine phosphonium ionic liquids was written by Brunel, Frederic;Lautard, Christelle;Garzino, Frederic;Giorgio, Suzanne;Raimundo, Jean M.;Bolla, Jean M.;Camplo, Michel. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2016.Recommanded Product: 1-Bromo-6-methoxyhexane This article mentions the following:
Staphylococcus aureus, a Gram pos. coccal bacterium is a major cause of nosocomial infection. We report the synthesis of new triphenylamine phosphonium ionic liquids which are able to self-assemble into multiwall nanoassemblies and to reveal a strong bactericidal activity (MIC = 0.5 mg/L) for Gram pos. bacteria (including resistant strains) comparable to that of standard antibiotics. Time kill, metabolism and fluorescence confocal microscopy studies show a quasi-instantaneously penetration of the nanoassemblies inside the bacteria resulting of a rapid blocking (30 min) of their proliferation. As confirmed by rezasurin reduction monitoring, these compounds strongly affect the bacterial metabolism and a Gram pos. vs. Gram neg. selectivity is clearly observed These fluorescent phosphonium ionic liquid might constitute a useful tool for both translocation studies and to tackle infectious diseases related to the field of implantol. In the experiment, the researchers used many compounds, for example, 1-Bromo-6-methoxyhexane (cas: 50592-87-5Recommanded Product: 1-Bromo-6-methoxyhexane).
1-Bromo-6-methoxyhexane (cas: 50592-87-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Recommanded Product: 1-Bromo-6-methoxyhexane
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary