Polarographic behavior of disubstituted derivatives of benzene or heterocycles. I. Substituted bromothiophenes was written by Person, Maurice;Mora, Raymond. And the article was included in Bulletin de la Societe Chimique de France in 1973.Category: bromides-buliding-blocks This article mentions the following:
The polarog. of the title compounds was studied at pH 2-15 in aqueous and anhydrous EtOH. In the group of 3- and 5-bromo-2-formyl-, 2-bromo-3-formyl-, and 3-bromo-2-acetylthiophenes, the wave for the splitting of the C-Br bond precedes that for the carbonyl group. Their oximes and thiosemicarbazones behave similarly. In the group of 4-bromo-2-formyl-, 2- and 5-bromo-3-formylthiophenes, the corresponding wave positions were reversed from the 1st group. The 5-bromothiophenes, substituted in the 2-position by CO2H, CO2Me, and CONH2, give C-Br scission waves which are identical in ethanolic and aqueous solutions depending on the pH. The effects of structure and the influence of substituents on the lability of the C-Br bond is discussed. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Category: bromides-buliding-blocks).
5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary