Stereospecific Overman Rearrangement of Substituted Cyclic Vinyl Bromides: Access to Fully Substituted α-Amino Ketones was written by Velasco-Rubio, Alvaro;Alexy, Eric J.;Yoritate, Makoto;Wright, Austin C.;Stoltz, Brian M.. And the article was included in Organic Letters in 2019.Computed Properties of C9H11BrO This article mentions the following:
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcs. providing tertiary allylic amines has been developed. The vinyl bromide used to control enantioselectivity in a preceding CBS reduction is utilized as a synthetic handle for the preparation of tertiary α-amino ketones and related derivatives in an asym. fashion. In the experiment, the researchers used many compounds, for example, 1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0Computed Properties of C9H11BrO).
1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C9H11BrO
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary