Zhu, Daqian et al. published their research in Chemistry – A European Journal in 2015 | CAS: 827-24-7

2-Bromo-4-methyl-6-nitroaniline (cas: 827-24-7) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 827-24-7

Relayed Regioselective Alkynylation/Olefination of Unsymmetrical Cyclic Diaryliodonium Species Catalyzed by Cu and Pd: Affording Fluorescent Cytotoxic Benzoxazoles was written by Zhu, Daqian;Liu, Panpan;Lu, Wenhua;Wang, Haiwen;Luo, Bingling;Hu, Yumin;Huang, Peng;Wen, Shijun. And the article was included in Chemistry – A European Journal in 2015.HPLC of Formula: 827-24-7 This article mentions the following:

Although cyclic diaryliodonium species have the potential to act as valuable synthons for cascade transformations, they still remain largely unexplored. The regioselectivity associated with unsym. cyclic diaryliodonium species has previously been known to pose a challenge. A regioselective relayed alkynylation and olefination of unsym. cyclic diaryliodonium species has been achieved by installation of a directing amide group. These relayed transformations were delayed until an oxazole ring had formed, delivering a series of unique fluorescent benzoxazoles. Moreover, some of these synthetic benzoxazoles showed apparent inhibitory activity against malignant cancer cells. Further confocal visualization revealed that benzoxazoles targeted cell nuclei. These findings might provide a novel structural scaffold to develop desirable anticancer agents. The synthesis of the target compounds was achieved by a reaction of [(carbonyl)amino]dibenziodolium trifluoromethanesulfonate salts (iodonium compounds) with (aryl)alkyne derivatives, such as 1-ethynyl-4-(methyl)benzene, 4-(ethynyl)benzoic acid ester, 2-methyl-3-butyn-2-ol, 3-butyn-1-ol. Alkene reactants included 2-propenoic acid 1,1-dimethylethyl ester, 1-penten-3-one, 1-ethenyl-2-nitrobenzene (nitro-styrene), 4-(ethenyl)benzonitrile. The title compounds thus formed included [(alkynyl)phenyl]benzoxazole derivatives and [(alkenyl)phenyl]benzoxazole derivatives In the experiment, the researchers used many compounds, for example, 2-Bromo-4-methyl-6-nitroaniline (cas: 827-24-7HPLC of Formula: 827-24-7).

2-Bromo-4-methyl-6-nitroaniline (cas: 827-24-7) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 827-24-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary