cis-Annulation of an oxazoline fragment to levoglucosenone and the synthesis of 4-substituted 3-amino-1,6-anhydro-3-deoxy-β-D-mannopyranose was written by Sharipov, Bulat T.;Davidova, Anna N.;Valeev, Farid A.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2022.Related Products of 128-08-5 This article mentions the following:
Chiral 2-trichloromethyl-oxazolines 4,5-cis-annulated to a carbohydrate fragment were synthesized on the basis of levoglucosenone. The synthesized compounds were converted by acid hydrolysis into 4-substituted 3-amino-1,6-anhydro-3-deoxy-β-D-mannopyranoses. Intramol. amination of allyl trichloroacetimidates by electrophilic reagents was used to construct the oxazoline ring. It was established that trichloroacetimidates containing an epoxide ring in α,β-positions spontaneously undergo re-cyclization with the formation of an oxazoline ring. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Related Products of 128-08-5).
1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Related Products of 128-08-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary