Transition-metal-free approaches to 2,3-diarylated indenones from 2-alkynylbenzaldehydes and phenols with tunable selectivity was written by Yao, Tuanli;Zhao, Shuaijing;Liu, Tao;Wu, Yuting;Ma, Yanhui;Li, Tao;Qin, Xiangyang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.COA of Formula: C9H6BrF3O2 This article mentions the following:
The first transition-metal-free regioselective synthesis of 2,3-diarylindenones via tandem annulation of 2-alkynylbenzaldehydes with phenols was described. Two different modes of reaction controlled by electronic effects and temperature furnished either “non-rearranged” or “rearranged” indenones in high selectivity. In the experiment, the researchers used many compounds, for example, Methyl 4-bromo-3-(trifluoromethyl)benzoate (cas: 107317-58-8COA of Formula: C9H6BrF3O2).
Methyl 4-bromo-3-(trifluoromethyl)benzoate (cas: 107317-58-8) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.COA of Formula: C9H6BrF3O2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary