Migratory Reductive Acylation between Alkyl Halides or Alkenes and Alkyl Carboxylic Acids by Nickel Catalysis was written by He, Jun;Song, Peihong;Xu, Xianfeng;Zhu, Shaolin;Wang, You. And the article was included in ACS Catalysis in 2019.Formula: C10H13BrO This article mentions the following:
A mild migratory reductive acyl cross-coupling has been achieved through NiH-catalyzed chainwalking and subsequent cross-coupling from two abundant starting materials, alkyl bromides, and carboxylic acids. This strategy allows the direct acylation of the benzylic sp3 C-H bond with high yield as a single regioisomer. As an alternative, the alkyl bromide could be replaced by the proposed olefin intermediate and com. available n-PrBr to achieve a remote hydroacylation process. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Formula: C10H13BrO).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Formula: C10H13BrO
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary