1,2-Bis(diphenylphosphino)ethane (dppe)/NBS: An Unprecedented Combination for Deoxygenation of Sulfoxides Under Mild Conditions was written by Joshi, Asha;Iqbal, Zafar;De, Saroj Ranjan. And the article was included in ChemistrySelect in 2022.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione This article mentions the following:
A novel, efficient and metal-free strategy for the deoxygenation of sulfoxides to sulfides was disclosed under mild conditions using dppe/NBS reagent system. Among several developed methods using phosphine based ligands, very few are convenient as most of them are confined to harsh reaction conditions, inseparable side products, moderate yields, and the use of costly and toxic reagents. The developed dppe/NBS promoted deoxygenation strategy tolerates a wide range of functional groups to afford good yields of desired sulfides. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Application In Synthesis of 1-Bromopyrrolidine-2,5-dione).
1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary