Spinnler, H.-E. et al. published their research in Applied Microbiology and Biotechnology in 1994 | CAS: 108940-96-1

3,5-Dibromo-4-methoxybenzaldehyde (cas: 108940-96-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Synthetic Route of C8H6Br2O2

Production of halogenated compounds by Bjerkandera adusta was written by Spinnler, H.-E.;de Jong, E.;Mauvais, G.;Semon, E.;le Quere, J.-L.. And the article was included in Applied Microbiology and Biotechnology in 1994.Synthetic Route of C8H6Br2O2 This article mentions the following:

The white-rot fungus Bjerkandera adusta produces volatile chlorinated Ph compounds The main compounds identified were 3-chloro-4-methoxybenzaldehyde (3-chloro-p-anisaldehyde), 3-chloro-4-methoxybenzyl alc. (3-chloro-p-anisyl alc.), 3,5-dichloro-4-methoxybenzaldehyde (3,5-dichloro-p-anisaldehyde), and 3,5-dichloro-4-methoxybenzyl alc. (3,5-dichloro-p-anisyl alc.). P-Anisaldehyde, veratraldehyde, and the corresponding alcs., p-anisyl alc. and veratryl alc., were produced simultaneously. Even with a very low concentration of Cl– in the medium (<10-5 M), chlorinated aromatic compounds were still observed Addition of Br– to the culture medium led to the production of brominated compounds: 3-bromo-4-methoxybenzaldehyde, 3-bromo-4-methoxybenzyl alc., 3,5-dibromo-4-methoxybenzaldehyde, and 3-bromo-5-chloro-4-methoxybenzaldehyde. These brominated compounds have not previously been reported as natural products. Although iodo-aromatic compounds were not produced by supplementation of the medium with I–, isovanillin was found in the culture broth under these conditions. This compound may be formed by substitution of the I intermediate by an OH group on C3 of the ring. CH2I2 or CH2ClI were also found. This is the 1st time that the production of halomethane has been related to the production of halogenated aromatic compounds All the strains tested have these capabilities. In the experiment, the researchers used many compounds, for example, 3,5-Dibromo-4-methoxybenzaldehyde (cas: 108940-96-1Synthetic Route of C8H6Br2O2).

3,5-Dibromo-4-methoxybenzaldehyde (cas: 108940-96-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Synthetic Route of C8H6Br2O2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary