Improved Flavodoxin Inhibitors with Potential Therapeutic Effects against Helicobacter pylori Infection was written by Galano, Juan J.;Alias, Miriam;Perez, Reyes;Velazquez-Campoy, Adrian;Hoffman, Paul S.;Sancho, Javier. And the article was included in Journal of Medicinal Chemistry in 2013.Application In Synthesis of 1-(3-Bromopropyl)-4-methoxybenzene This article mentions the following:
A variety of electron-deficient chromenes and styrenes and nitrobenzooxadiazolyl thioethers and other compounds were tested (and in some cases prepared) as selective inhibitors of flavodoxin in Helicobacter pylori for potential use in the treatment of gastric ulcer and prevention of stomach cancer with fewer side effects and reduced susceptibilities to drug resistance; their inhibition of flavodoxin and of Helicobacter pylori and their cytotoxicities were determined For example, (E)-ArCH:CHNO2 (Ar = 2-F-5-F3CC6H3, 4-Cl-2,6-F2C6H2) inhibited H. pylori with IC50 values of 0.53 μM and therapeutic indexes of 38 and 15, resp. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Application In Synthesis of 1-(3-Bromopropyl)-4-methoxybenzene).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Application In Synthesis of 1-(3-Bromopropyl)-4-methoxybenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary