Highly selective electroreductive linear dimerization of electron-deficient vinylarenes was written by Ning, Shulin;Zheng, Lianyou;Bai, Ya;Wang, Shutao;Wang, Siyu;Shi, Lingling;Gao, Qiansong;Che, Xin;Zhang, Zhuoqi;Xiang, Jinbao. And the article was included in Tetrahedron in 2021.HPLC of Formula: 474709-71-2 This article mentions the following:
A direct electroreductive dimerization of electron-deficient vinylarenes R1R2C:CR3R4 (R1 = Ph, 4-NCC6H4, pyridin-4-yl, etc., R2 = R3 = R4 = H; R1 = 4-EtO2CC6H4, R2 = Me, Ph, R3 = R4 = H; R1 = 4-MeO2CC6H4, R2 = H, R3 = Me, R4 = H, Me; etc.) for the synthesis of 1,4-diarylbutanes R1R2CH-CR3R4-CR3R4-CHR1R2 as been developed using a simple undivided cell with inexpensive carbon electrodes at room temperature The control and deuterium-labeling experiments of electroreductive dimerization suggest that the hydrogen source comes from the solvent CH3CN. This protocol provides a mild and efficient route for the construction of C-C bond in moderate to good yields with high regioselectivity and broad substrate scope. In the experiment, the researchers used many compounds, for example, Ethyl 4-bromo-2-fluorobenzoate (cas: 474709-71-2HPLC of Formula: 474709-71-2).
Ethyl 4-bromo-2-fluorobenzoate (cas: 474709-71-2) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 474709-71-2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary