De Novo Synthesis of Phenols and Naphthols through Oxidative Cycloaromatization of Dienynes was written by Rong, Ming-Guang;Qin, Tian-Zhu;Liu, Xin-Rui;Wang, Hong-Fa;Zi, Weiwei. And the article was included in Organic Letters in 2018.Related Products of 85118-24-7 This article mentions the following:
In this work, a rhodium-catalyzed oxidative cycloaromatization of dienynes, which provides a highly straightforward and efficient way to access polysubstituted naphthols and phenols under mild conditions, is described. Challenged electron-withdrawing groups are well tolerated in this protocol, and late-stage Ph ring formation is demonstrated. In the experiment, the researchers used many compounds, for example, 2-Bromo-4-(trifluoromethyl)benzaldehyde (cas: 85118-24-7Related Products of 85118-24-7).
2-Bromo-4-(trifluoromethyl)benzaldehyde (cas: 85118-24-7) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Related Products of 85118-24-7
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary