Synthetic Route of 630-17-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 630-17-1, name is 1-Bromo-2,2-dimethylpropane, This compound has unique chemical properties. The synthetic route is as follows.
40 This method was used for the synthesis of neopentylphenyl sulfide, 5h.1-Bromo-2,2-dimethyl propane (3.02 g, 20 mmol), aqueousbenzenethiolate (20 mmol), and Aliquat 336 (0.033 mol equiv)were added to a 2-neck round-bottom flask under nitrogen. Themixture was heated at 70 C with vigorous stirring for 16 h. After themixture had cooled to room temperature, the organic layer wasseparated and the aqueous phase was extracted with two 20 mLportions of diethyl ether. The combined organic phases were washedwith 20 mL of 10% aqueous sodium chloride and dried overmagnesium sulfate. After removal of the solvent, the resulting residualoil was distilled using a Kugelrohr apparatus to give neopentyl phenylsulfide, bp 145-147 (0.1 mm. Hg).
The chemical industry reduces the impact on the environment during synthesis 1-Bromo-2,2-dimethylpropane. I believe this compound will play a more active role in future production and life.
Reference:
Article; O’Mahony, Graham E.; Eccles, Kevin S.; Morrison, Robin E.; Ford, Alan; Lawrence, Simon E.; Maguire, Anita R.; Tetrahedron; vol. 69; 47; (2013); p. 10168 – 10184;,
Bromide – Wikipedia,
bromide – Wiktionary