As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 58971-11-2 name is 3-Bromophenethylamine, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. 58971-11-2
A solution of 2- (3-bromophenyl) ethylamine (2 g, 10 mmol)Was dissolved in dichloromethane (30 mL)To this was added triethylamine (3 mL, 20.99 mmol) andAcetic anhydride (2 mL, 20.99 mmol).The reaction mixture was stirred at room temperature overnight, followed by water (50 mLx3), brine (50 mL x 3), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product (2.42 g, 100%).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-Bromophenethylamine, and friends who are interested can also refer to it.
Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Jiatuo Sciences Corporation; Xi Ning; Wang Ruyong; Wang Liang; (112 pag.)CN104016979; (2017); B;,
Bromide – Wikipedia,
bromide – Wiktionary