Adding a certain compound to certain chemical reactions, such as: 1435-51-4, name is 1,3-Dibromo-5-fluorobenzene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1435-51-4, 1435-51-4
To a solution of 1,3-dibromo-5-fluorobenzene (5.105 g, 20.11 mmol) in ether(50 ml) in a dry ice-acetone bath was added 1.6M butyllithium in hexanes (12.5 ml,20.0 mmol). After 2 h benzaldehyde (2.287 g, 21.55 mmol) was added and themixture was allowed to w
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,3-Dibromo-5-fluorobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; SCHERING CORPORATION; WO2006/14762; (2006); A1;,
Bromide – Wikipedia,
