In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2789-89-1 as follows. COA of Formula: C14H8Br2
General procedure: The photocatalyst [Ir(dF-CF3-ppy)2(dtbpy)]PF6 (PC-1) (11.2 mg, 0.01 mmol, 2.0 mol%) wasadded to an oven-dried Schlenk tube containing a magnetic stirring bar and anhydrous ethylacetate (2.5 mL, 0.2 M) was added under argon. In the absence of light, the enone (0.5 mmol,1.0 equiv) and the alkyne (1.0 mmol, 2.0 equiv) were added under an argon stream. Theresulting solution was degassed using three freeze-pump-thaw cycles and the tube was finallybackfilled with argon. The reaction mixture was allowed to stir at room temperature for 24 hunder irradiation with visible light from two 30 W Kessil LEDs (lambdamax = 455 nm, see chapter 1.2).The solvent was evaporated and the crude reaction products were purified by columnchromatography over silica gel (dry load of crude material, pentane/EtOAc or pentane/diethylether mixtures as eluent) to afford products 6a-6e, 9a-9e and 10.
According to the analysis of related databases, 2789-89-1, the application of this compound in the production field has become more and more popular.
Reference:
Article; Strieth-Kalthoff; Henkel, Christian; Teders, Michael; Kahnt, Axel; Knolle, Wolfgang; Gomez-Suarez, Adrian; Dirian, Konstantin; Alex, Wiebke; Bergander; Daniliuc, Constantin G.; Abel; Guldi, Dirk M.; Glorius; Chem; vol. 5; 8; (2019); p. 2183 – 2194;,
Bromide – Wikipedia,
bromide – Wiktionary