Wang, Siyuan; Zhou, Yangkun; Huang, Hanmin published the artcile< Palladium-Catalyzed Tandem Carbonylative Diels-Alder Reaction for Construction of Bridged Polycyclic Skeletons>, Category: bromides-buliding-blocks, the main research area is aldehyde halomethylaryl diastereoselective regioselective carbonylative Diels Alder alkene; bridged bicyclic lactone stereoselective preparation.
A palladium-catalyzed tandem carbonylative lactonization and Diels-Alder cycloaddition reaction between aldehyde-tethered benzyl halides I (R1 = H, X = Cl, Br; R1 = 4-Cl, 3-Br, 5-MeO, etc., X = Br) and alkenes R2R3C:CHR4 [R2 = H, n-BuO, ClCH2CH2O, BocNH, Ph, 2-MeC6H4, 4-ClC6H4, etc., R3 = R4 = H; R2 = Ph, R3 = Me, R4 = H; R2R4 = OCH2CH2, (CH2)3, (CH2)6; etc.] has been developed. A range of alkenes and aldehyde-tethered benzyl halides bearing different substituents can be successfully transformed into the corresponding bridged polycyclic compounds II in good yields. This strategy provides a unique approach to complex lactone-containing bridged polycyclic compounds
Organic Letters published new progress about Aldehydes, halo Role: RCT (Reactant), RACT (Reactant or Reagent). 337536-14-8 belongs to class bromides-buliding-blocks, and the molecular formula is C9H8Br2O2, Category: bromides-buliding-blocks.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary