Chu, Duc; Ellman, Jonathan A. published the artcile< Three-Component Friedel-Crafts Transformations: Synthesis of Alkyl and Alkenyl Trifluoromethyl Sulfides and Alkenyl Iodides>, Reference of 576-83-0, the main research area is trifluoromethyl arylalkenyl sulfide diastereoselective preparation; arene alkyne trifluoromethyl benzenesulfonamide regioselective three component Friedel Crafts; trifluoromethylthio alkylarene diastereoselective preparation; alkene arene trifluoromethyl benzenesulfonamide regioselective three component Friedel Crafts; iodoalkenyl arene preparation; iodosuccinamide alkyne arene regioselective three component Friedel Crafts reaction.
Straightforward and mild hexafluoroisopropanol (HFIP)-mediated, metal-free, three-component Friedel-Crafts approaches were reported for the synthesis of alkenyl and alkyl trifluoromethyl sulfides from arenes, (PhSO2)2NSCF3 and alkynes or alkenes, resp. The transformations proceeded with high regio- and stereochem. control via the initial formation of cationic thiirenium and thiiranium intermediates, resp., followed by Friedel-Crafts reactions with the arene. A mechanistically related three-component synthesis of alkenyl iodides from arenes, alkenes and N-iodosuccinimide was reported.
Organic Letters published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Reference of 576-83-0.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary