Li, Wen-Xin; Yang, Bo-Wen; Ying, Xuan; Zhang, Zhuo-Wen; Chu, Xue-Qiang; Zhou, Xiaocong; Ma, Mengtao; Shen, Zhi-Liang published the artcile< Nickel-Catalyzed Direct Cross-Coupling of Diaryl Sulfoxide with Aryl Bromide>, Computed Properties of 576-83-0, the main research area is biaryl preparation; diaryl sulfoxide aryl bromide cross coupling nickel catalyst.
The direct cross-couplings of diaryl sulfoxides with aryl bromides via C-S bond cleavage could be readily accomplished using nickel(II) as the catalyst, 1,2-bis(diphenylphosphino)ethane (dppe) as the ligand, and magnesium turnings as the reducing metal in THF, leading to the corresponding biaryls RR1 [R = Ph, 4-MeC6H4, 2-naphthyl, etc.; R1 = 4-MeOC6H4, 2-pyridyl, benzofuran-5-yl, etc.] in moderate to good yields. The reaction exhibited a broad substrate scope and could be applied to a gram-scale synthesis. The ”one-pot” reaction, which avoided the utility of presynthesized and moisture-labile organometallic compounds, was operationally simple and step-economic.
Journal of Organic Chemistry published new progress about Aromatic compounds, sulfoxides Role: RCT (Reactant), RACT (Reactant or Reagent). 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Computed Properties of 576-83-0.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary