Yang, Lei; Xu, Wen-Qiang; Liu, Tao; Wu, Yichen; Wang, Biqin; Wang, Peng published the artcile< Concise synthesis and applications of enantiopure spirobiphenoxasilin-diol and its related chiral ligands>, Category: bromides-buliding-blocks, the main research area is enantiopure spirobiphenoxasilin diol phosphonate preparation crystal mol structure; chiral ligand enantiopure spirobiphenoxasilin diol preparation catalyst asym reaction.
The development of chiral architectures for chiral ligand and catalyst discovery is essential for asym. catalysis. Herein, authors report the concise synthesis of a Si-centered spirocyclic skeleton, spirobiphenoxasilin-diol (SPOSiOL), and its derived chiral ligands. Using the chem. resolution method, the optical SPOSiOL could be obtained in high yield on a gram scale. Preliminary studies indicated that this ligand scaffold has great potential in transition metal-catalyzed asym. reactions. This finding further highlights that the Si-centered spirocyclic scaffolds are of great value in asym. catalysis.
Chemical Communications (Cambridge, United Kingdom) published new progress about Crystal structure. 135999-16-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2, Category: bromides-buliding-blocks.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary