Thorve, Pradip Ramdas; Maji, Biplab published the artcile< Deaminative Olefination of Methyl N-Heteroarenes by an Amine Oxidase Inspired Catalyst>, Reference of 3959-07-7, the main research area is diaryl olefin preparation diastereoselective; methyl heteroarene primary amine deaminative olefination phenanthrolinedione catalyst.
The bioinspired o-quinone cofactor catalyzed aerobic primary amine ArCH2NH2 (Ar = Ph, 2-chlorophenyl, furan-2-yl, etc.) dehydrogenation for a cascade olefination reaction with nine different Me N-heteroarenes, including pyrimidines such as 4-Me pyrimidine, N-benzyl-4-methylpyrimidin-2-amine and N,N-dibenzyl-4-methylpyrimidin-2-amine, 2-methylpyrazine, pyridines such as 4-methylpyridine, 5-bromo-2-methylpyridine, 2-methylpyridine, etc.; quinolines such as 2-methylquinoline, 2,6-dimethylquinoline, 6-methoxy-2-methylquinoline and 4-methylquinoline, 2-methylquinoxaline, benzimidazoles such as 1-benzyl-2-methyl-1H-1,3-benzodiazole and 1-benzyl-5,6-dichloro-2-methyl-1H-1,3-benzodiazole, 2-methyl-1,3-benzoxazole, 2-methyl-1,3-benzothiazole and 2,4,6-trimethyl-1,3,5-triazine were explored. An o-quinone catalyst phd (1,10-phenanthroline-5,6-dione) combined with a Bronsted acid such as TfOH catalyzed the reaction. N-Heteroaryl stilbenoids RCH=CHAr (R = pyridin-2-yl, pyrimidin-4-yl, 1,3-benzoxazol-2-yl, etc.) were synthesized in high yields and (E)-selectivities under mild conditions using oxygen (1 atm) as the sole oxidant without the need of transition-metal salt, ligand, stoichiometric base, or oxidant.
Organic Letters published new progress about Aryl alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Reference of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary